NON-OBSTRUCTIVE CORONARY ARTERY DISEASE: ANALYSIS AND PROGNOSIS
Aim. To evaluate the prevalence, risk factors and results of non-invasive tests and cardiac outcomes in patients with angina and non-obstructive coronary artery disease (CAD). Results. Non-obstructive CAD was detected in 36.3% patients (21.4% of them coronary angiography (CA) was performed due to valve pathology). 14.9% of patients were more likely to have atypical chest pain. Subjects were more likely to be elderly women (58%) with dyslipidemia and arterial hypertension. Men with non-obstructive CAD were more likely to be smokers and alcohol users. 83.9% of patients were with normal left ventricular ejection fractions, left ventricle ejection fraction (LVEF) >50%. Non-invasive tests were performed in 512 (65.5%) patients, 248 (48.4%) were found pathologic. During the median follow-up of 1 year, a total of 20 (2.0%) acute coronary syndromes occurred. Conclusions. 1) Non-obstructive CAD was detected in more than one third of subjects. Non-obstructive CAD was more often diagnosed for women, they were older than men. 2) These patients’ the most common risk factors: arterial hypertension, dyslipidemia, obesity, family history of CAD. About 15% of patients had diabetes, nearly 17% used tobacco. Compared to men, women were more likely to have dyslipidemia and arterial hypertension. Men were more likely to use tobacco and alcohol. Most patients were diagnosed with stable angina. Atypical angina was more common clinically. 3) Non-invasive tests were performed in more than half of the patients (mostly veloergometry – VEM), of which about half were found to be pathological. Echocardiography revealed good LVEF for most patients. 4) An increased risk of future cardiovascular events has been observed in patients with non-obstructive CAD.