• Eglė Jasaitytė Šeimos klinika „Saulenė“
  • Simona Vaičė Šeimos klinika „Saulenė“
  • Ovidija Šriupšienė LSMU MA Šeimos medicinos klinika
  • Olga Vasiliauskienė LSMU MA Šeimos medicinos klinika
Keywords: nonsteroidal anti-inflammatory drugs, knowledge about medications, adverse effects of medicine


Nonsteroidal anti-inflammatory drugs (NAID) are some of the most widely used medications which alleviate pain and have anti-inflammatory and antipyretic effects. NAID are consumed every day by huge numbers of people around the world who disregard the indications and side effects, as well as the peculiarities of use of these drugs. Methods. 423 respondents who used NSAIDs were included in the survey. Data were collected using an anonymous questionnaire. The Microsoft Excel 2019 and IBM SPSS 22.0 programs were used for statistical analysis. Data were considered statistically significant when the probability of a mistake is less than 0.05 (p<0.05). Results. The most commonly used NSAID was ibuprofen, 67.9% of all participants. Ibuprofen was predominantly used in 18–39 age group while diclofenac – in 60 + years old group. The most common reasons for taking NSAIDs included headache, back pain and common cold. 84.4% of all respondents took one active ingredient of NSAIDs at one time. 74.4% took NSAIDs less than 2 weeks. Proton pump inhibitors (PPIs) were used together with NSAIDs by 22.9% of respondents. Increased usage of PPIs was associated with the daily use of NSAIDs. 67.2% of all participants who had gastrointestinal tract disorders used PPIs. Almost half of the respondents (44.4%) chose NSAID by doctor advice. Adverse effects occurred in 14.7% of all participants. The most common side effect was gastrointestinal tract disorder. Respondents who used 3 or more active substances at one time more frequently felt side effects (35.7%). Using NSAID by doctor advice was associated with reduced appearance of adverse effects. 35% of respondents had good knowledge about NSAIDs, 59.1% mediocre and 5.9% poor knowledge about NSAIDs. 79.4% didn’t know the maximum dose of ibuprofen and only 17.3% knew that the effect of diclofenac to stomach doesn’t belong to medication form. Conclusions. The most commonly used NSAIDs were ibuprofen, nimesulide and diclofenac. The dominant reasons for taking NSAIDs were headache, back pain and common cold. Most of respondents took one active ingredient of NSAIDs at one time. A quarter of all respondents used PPIs with NSAIDs. Almost half of the patients decided on NSAIDs by doctor’s recommendations. Adverse effects occurred in less than a quarter of all participants. Almost 90% of respondents suffered from gastrointestinal tract disorders. The majority of respondents had sufficient knowledge about NSAIDs.