ENDOMETRIAL RECEPTIVITY AND LUTEAL PHASE IN MEDICALLY ASSISTED REPRODUCTION

  • Laima Maleckienė LSMU MA Akušerijos ir ginekologijos klinika
  • Joana Trečiokaitė LSMU MA Medicinos fakultetas
  • Ugnė Kryžiūtė LSMU MA Medicinos fakultetas
  • Eglė Drejerienė LSMU MA Akušerijos ir ginekologijos klinika
  • Rūta Bartašienė LSMU MA Akušerijos ir ginekologijos klinika
  • Agnė Kozlovskaja-Gumbrienė LSMU MA Akušerijos ir ginekologijos klinika
DOI: https://doi.org/10.37499/LAG.1143
Keywords: assisted reproductive technology, progesterone, embryo transfer, luteal phase support, pregnancy rate

Abstract

This review focuses on the existing literature on endometrial receptivity, embryo implantation and luteal phase support in medically assisted reproduction. The electronic databases of “PubMed” (“Medline”), “Embase” and “Cochrane” were searched using the relevant keywords. 36 English-language articles with fulltext access published during last decade were selected for review. It is well established that after controlled ovarian hyperstimulation, the production of endogenous progesterone is insufficient. Therefore, in the fresh cycle luteal phase support is essential to improve reproductive outcomes. Transfer of frozen/thawed embryos can be performed in a programmed cycle, a natural menstrual cycle, a modified natural cycle, a stimulated cycle. Luteal phase support should be individualised to maximise the efficacy and safety of assisted reproductive technology.

Published
2023-03-24
Issue
Vol 26 No 1 (2023): Lithuanian Obstetrics & Gynecology
Section
Continuous education