VULVAR LICHEN SCLEROSUS AND ATROPHICUS ASSOCIATIONS WITH HPV INFECTION AND VULVAR INTRAEPITHELIAL NEOPLASIA

Abstract

Vulvar lichen sclerosis and atrophicus is a chronic mucocutaneous inflammatory dermatosis that may lead to damage of the vulva, sexual dysfunction, and general quality of life deterioration. Common symptoms are flat, ivory-colored spots, burning itching, pain, redness, dysuria, and dyspareunia. The disease is also associated with the risk of developing HPV infection and vulvar cancer. The article describes the clinical case, signs, pathogenesis, clinical symptoms, treatment options, and associations with HPV infection and vulvar intraepithelial neoplasia.